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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Descripte se compraestas de Cialis
InteractionDetails
grapefruit- increase blood pressure
Grapefruit juice- increases blood pressure
High-fat meal
Lopinavir
arton- worsen side effects

C.

Cialis (tadalafil) can interact with certain foods and beverages, such as grapefruit, which may reduce its effectiveness. It is advisable to avoid these types of foods and beverages while taking Cialis.

D.

Tadalafil Citrate

Tadalafil citrate is a phosphodiesterase type 5 inhibitor that improves blood flow to the penis. This medicine should be used by men who have erectile dysfunction (ED) or low blood pressure, which can cause an erection for a prolonged period. You may need to take tadalafil for up to 3 hours after each sexual activity. If you do not understand the dose of tadalafil you may have a higher risk of side effects.

Tadalafil is used to treat male impotence (impotence that does not go away) and to treat benign prostatic hyperplasia (BPH).

It is also used to treat pulmonary arterial hypertension and high blood pressure in the lungs (high blood pressure in the right side of the heart).

Tadalafil can be used to treat the symptoms of erectile dysfunction.

How Does Tadalafil Work?

Tadalafil is a phosphodiesterase type 5 inhibitor. This is a medicine that works by helping the body in an increased amount of blood to the penis. The increased blood flow helps to make the penis bigger and therefore allows for an erection.

The blood pressure of the blood vessels is increased and the pressure inside them is reduced. The flow of blood inside the penis is increased and then reduced. This allows blood to flow into the penis. This helps to produce an erection, which can last for a long time.

Tadalafil is also used to treat pulmonary arterial hypertension (PAH) (high blood pressure in the arteries of the lungs).

What Are the Side Effects of Tadalafil?

The most common side effects of tadalafil may include headache, flushing, indigestion, nasal congestion, and dizziness. Some people may also experience more serious side effects such as sudden vision loss, hearing loss, or an erection that lasts longer than 4 hours. If you experience these serious side effects, seek medical help right away. These side effects usually go away on their own, but if they persist or become severe, you should talk to a doctor.

How Can I Take Tadalafil for ED?

You can take tadalafil for erectile dysfunction if your doctor recommends you take it. You should not take tadalafil for erectile dysfunction unless it is absolutely necessary. You may need to take tadalafil for more than 3 days. You can take it for up to 5 days. You should not take tadalafil for erectile dysfunction if you:

  • have diabetes
  • have a heart condition
  • are over 65 years old
  • have ever had a heart attack
  • have recently had an eye surgery
  • are under 18 years old
  • have recently had a stroke
  • have recently had a blood clot
  • have high blood pressure
  • have ever had a kidney problem
  • have a serious heart problem
  • have ever had an irregular heartbeat
  • have a heart disease or heart disease, such as a heart attack, or a heart disease.

If you are not sure how to take tadalafil, you can take it as directed by your doctor. It is not known if tadalafil will affect your sex life or if your sex life will improve. If you have any questions or concerns, talk to your doctor.

If you are using tadalafil to treat erectile dysfunction, your doctor will determine whether you should take tadalafil for this or any other condition. Tadalafil can cause side effects, including:

  • headaches
  • flushing
  • indigestion
  • nausea
  • heartburn
  • heartburn with stomach pain
  • nosebleeds
  • heartburn with back pain
  • heartburn with ringing in your ears
  • increased pressure inside the chest
  • blood pressure changes
  • swelling of the feet or ankles

If you are using tadalafil to treat ED, your doctor will evaluate your medical condition and check your blood pressure levels. If your blood pressure is low or not high enough, your doctor will adjust the dose of tadalafil.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Read more about Cialis's side effects.otc tadalafil review

This medication can cause potentially serious adverse reactions when taken at high doses. These reactions may include:

  • Trouble getting or maintaining an erection
  • Swelling of the face/tongue/throat
  • Swelling of the hands/feet

These are side effects that can:

  • Have physical signs such as pain in your chest with vision changes.
  • May cause a sudden decrease or loss of hearing
  • Have shortness of breath
  • Have lower blood pressure (high blood pressure)
  • May be of greatest concern if you have a history of glaucoma, angle-closure glaucoma, or other medical conditions.

As with all prescription medications, be sure to inform your doctor of any medical conditions you currently manage. Tell your health care provider that you are taking this medication.

In addition, let your doctor know if you are pregnant or plan to become pregnant. If you are, you should not take this medication. Your doctor should not start you on nitrates or inhale cannabis during treatment unless your doctor starts you on nitrates.

Read more about how Cialis can affect your vision.

In addition, let your doctor know if you are having an allergic reaction to Cialis or similar medications. As with all prescription medications, inform your doctor about any and all medications you are taking before using Cialis. Cialis can also affect the way other medications work, increasing the risk of side effects.

As with all prescription medications, be sure to ask your doctor if you have any questions. You should always hesitate to give in toCONCLUSionioning this medication can have a potentially serious effect on your ability to perform the assigned sex act.

Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

for chest pain or use Rectogesic ointment?

• Nicorandil (Ikorel), used to treat angina

• Cimetidine, used to treat stomach or duodenal (peptic) ulcers

• Theophylline, used to treat asthma

• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

• Anti-fungals such as itraconazole and ketoconazole

• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

• Recreational drugs:- amyl nitrate (poppers)

If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

Read available consultation questionnaire

What is Tadalafil?

Tadalafil is a prescription medication that is used to treat erectile dysfunction (ED) and pulmonary arterial hypertension.

It is also used to treat combination drug-drug plan (CDPP) caused by bacteria.

Tadalafil works by increasing the ability to make it to enable the flow of blood to the penis.

It helps the effects of the medication to be made better.

How do I take Tadalafil?

You should take the tablets exactly as possible by drinking about one one-quarter (not so much as touched) glass of water with a mouthpiece. You must take the tablets about an hour before you plan to have sex. You must complete a medical consultation questionnaire that asks for any questions that the doctor can specify.

There are several ways of taking Tadalafil; it is possible to take Tadalafil with other medicines such as Sporanox, Ajoane and Risperidone.

There are two ways of taking Tadalafil;- tablet - as an oral pill or a vaginal capsule

Daily tablet

You can take one tablet on/with each of the following medicines:-

Rosenthalia (oxcarbazepine)

St. John’s wort (prazosin)

Is there any other medical information that my doctor should know?

If your doctor knows you they will ask you in a medical questionnaire. Then they will ask you in a medical questionnaire whether the medicine is safe for you to take.

You can then write to our doctor in the “Is there any other medical information that my doctor should know?” section on the medical questionnaire.

You should take the tablets exactly as you may take a pill with a mouthpiece.